Product Description
Doxycycline is used to treat infections caused by bacteria, including pneumonia and other respiratory tract infections; certain infections of the skin or eye; infections of the lymphatic, intestinal, genital, and urinary systems; and certain other infections that are spread by ticks, lice, mites, infected animals, or contaminated food and water. It is also used along with other medications to treat acne. Doxycycline is also used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack), in people who may have been exposed to anthrax in the air, and to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). It is also used to prevent malaria. Doxycycline can also be used in people who cannot be treated with penicillin to treat certain types of food poisoning. Doxycycline (Oracea) is used only to treat pimples and bumps caused by rosacea (a skin disease that causes redness, flushing, and pimples on the face). Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne. It works to treat rosacea by decreasing the inflammation that causes this condition. (Sourced from: https://medlineplus.gov/druginfo/meds/a682063.html)
Mechanisms of Action: MMP Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Anthrax | Rickettsia Infections | Respiratory Tract Infections | Amebiasis | Malaria | Erythema | Borrelia Infections | Lyme Disease
Known Adverse Events: Sunburn | Urticaria | Tooth Discoloration | Anemia | Anemia, Hemolytic | Superinfection | Pregnancy Outcomes | Anorexia | Diarrhea
Company: Galderma
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, China, Lao, United States
Active Clinical Trial Count: 7
Highest Development Phases
Phase 3: Communicable Diseases
Phase 2: Coronary Disease|Healthy Volunteers|Injuries/wounds Unspecified|Pneumonia
Phase 1: Anus Diseases|Brucellosis|Chancroid|Chlamydia Infections|Cholera|Gas Gangrene|Gonorrhea|Leptospirosis|Mycoplasma Infections|Oncology Solid Tumor Unspecified|Plague|Psittacosis|Q Fever|Relapsing Fever|Salpingitis|Sarcoma|Syphilis|Tetanus|Trachoma|Tularemia|Urethritis|Yaws
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
RiCS | P3 |
Recruiting |
Communicable Diseases |
2025-08-31 |
|
2022P001117 | P2 |
Active, not recruiting |
Injuries/wounds Unspecified|Healthy Volunteers |
2024-10-02 |
|
Safety and Efficacy of DâPLEX in the Prevention of Post Abdominal Surgery Incisional Infection. | P3 |
Active, not recruiting |
Unknown |
2022-11-30 |
|
Safety and Efficacy of DâPLEX in the Prevention of Post Abdominal Surgery Incisional Infection. | P3 |
Completed |
Unknown |
2022-08-08 |