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Doxycycline

Alternative Names: doxycycline, vibramycin, monodox, oracea, periostat, doryx, doxycyclin, COL-101, doxychel, doxiciclina, acticlate, acticlate cap, doxy 100, atridox, lymepak, doxy-lemmon, doxy 200, vibra-tabs, doxycyclate hyclate, targadox, okebo, mondoxyne nl, Ocudox, doxycycline hyclate
Latest Update: 2025-01-21
Latest Update Note: Clinical Trial Update

Product Description

Doxycycline is used to treat infections caused by bacteria, including pneumonia and other respiratory tract infections; certain infections of the skin or eye; infections of the lymphatic, intestinal, genital, and urinary systems; and certain other infections that are spread by ticks, lice, mites, infected animals, or contaminated food and water. It is also used along with other medications to treat acne. Doxycycline is also used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack), in people who may have been exposed to anthrax in the air, and to treat plague and tuleramia (serious infections that may be spread on purpose as part of a bioterror attack). It is also used to prevent malaria. Doxycycline can also be used in people who cannot be treated with penicillin to treat certain types of food poisoning. Doxycycline (Oracea) is used only to treat pimples and bumps caused by rosacea (a skin disease that causes redness, flushing, and pimples on the face). Doxycycline is in a class of medications called tetracycline antibiotics. It works to treat infections by preventing the growth and spread of bacteria. It works to treat acne by killing the bacteria that infects pores and decreasing a certain natural oily substance that causes acne. It works to treat rosacea by decreasing the inflammation that causes this condition. (Sourced from: https://medlineplus.gov/druginfo/meds/a682063.html)

Mechanisms of Action: MMP Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: Anthrax | Rickettsia Infections | Respiratory Tract Infections | Amebiasis | Malaria | Erythema | Borrelia Infections | Lyme Disease

Known Adverse Events: Sunburn | Urticaria | Tooth Discoloration | Anemia | Anemia, Hemolytic | Superinfection | Pregnancy Outcomes | Anorexia | Diarrhea

Company: Galderma
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Doxycycline

Countries in Clinic: Australia, China, Lao, United States

Active Clinical Trial Count: 7

Highest Development Phases

Phase 3: Communicable Diseases

Phase 2: Coronary Disease|Healthy Volunteers|Injuries/wounds Unspecified|Pneumonia

Phase 1: Anus Diseases|Brucellosis|Chancroid|Chlamydia Infections|Cholera|Gas Gangrene|Gonorrhea|Leptospirosis|Mycoplasma Infections|Oncology Solid Tumor Unspecified|Plague|Psittacosis|Q Fever|Relapsing Fever|Salpingitis|Sarcoma|Syphilis|Tetanus|Trachoma|Tularemia|Urethritis|Yaws

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

RiCS

P3

Recruiting

Communicable Diseases

2025-08-31

2022P001117

P2

Active, not recruiting

Injuries/wounds Unspecified|Healthy Volunteers

2024-10-02

Safety and Efficacy of D‐PLEX in the Prevention of Post Abdominal Surgery Incisional Infection.

P3

Active, not recruiting

Unknown

2022-11-30

Safety and Efficacy of D‐PLEX in the Prevention of Post Abdominal Surgery Incisional Infection.

P3

Completed

Unknown

2022-08-08

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