Product Description
Docetaxel injection is used to treat advanced or metastatic (cancer that has spread) breast cancer in patients who have previously received other cancer medicines that did not work well. It is also used together with other medicines (eg, cyclophosphamide, doxorubicin) to treat node-positive breast cancer that can be removed by surgery. Docetaxel belongs to the group of medicines called antineoplastics (cancer medicines). It interferes with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal cells may also be affected by docetaxel, other unwanted effects will also occur. (Sourced from: https://www.mayoclinic.org/drugs-supplements/docetaxel-intravenous-route/side-effects/drg-20068305?p=1)
Mechanisms of Action: Mitosis Inhibitor,Tubulin Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Adenocarcinoma | Breast Cancer | Esophageal Cancer | Gastrointestinal Cancer | Head and Neck Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Oncology Solid Tumor Unspecified | Prostate Cancer | Small Cell Carcinoma | Small Cell Lung Cancer | Squamous Cell Carcinoma | Oncology Unspecified | Adenocarcinoma | Breast Cancer | Esophageal Cancer | Gastrointestinal Cancer | Head and Neck Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Oncology Solid Tumor Unspecified | Prostate Cancer | Small Cell Carcinoma | Small Cell Lung Cancer | Squamous Cell Carcinoma | Oncology Unspecified | Adenocarcinoma | Breast Cancer | Esophageal Cancer | Gastrointestinal Cancer | Head and Neck Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Oncology Solid Tumor Unspecified | Prostate Cancer | Small Cell Carcinoma | Small Cell Lung Cancer | Squamous Cell Carcinoma | Oncology Unspecified | Adenocarcinoma | Breast Cancer | Esophageal Cancer | Gastrointestinal Cancer | Head and Neck Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Oncology Solid Tumor Unspecified | Prostate Cancer | Small Cell Carcinoma | Small Cell Lung Cancer | Squamous Cell Carcinoma | Oncology Unspecified | Adenocarcinoma | Breast Cancer | Esophageal Cancer | Gastrointestinal Cancer | Head and Neck Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Oncology Solid Tumor Unspecified | Prostate Cancer | Small Cell Carcinoma | Small Cell Lung Cancer | Squamous Cell Carcinoma | Oncology Unspecified | Adenocarcinoma | Breast Cancer | Esophageal Cancer | Gastrointestinal Cancer | Head and Neck Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Oncology Solid Tumor Unspecified | Prostate Cancer | Small Cell Carcinoma | Small Cell Lung Cancer | Squamous Cell Carcinoma | Oncology Unspecified | Breast Cancer | Lung Cancer | Non-Small-Cell Lung Cancer | Prostate Cancer | Small Cell Lung Cancer | Oncology Unspecified
Known Adverse Events: Dysgeusia | Pain Unspecified | Alopecia | Mucositis | Anemia | Thrombocytopenia | Neutropenia | Cross Infection | Myalgia | Dyspnea | Anorexia | Asthenia | Constipation | Diarrhea | Febrile Neutropenia
Company: Sanofi
Company Location: PARIS I0 75008
Company CEO: Paul Hudson
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, China, Colombia, Czech Republic, Denmark, Finland, France, Germany, Greece, Hong Kong, Hungary, India, Ireland, Israel, Italy, Japan, Korea, Malaysia, Mexico, Netherlands, New Zealand, Poland, Puerto Rico, Romania, Russia, Singapore, Spain, Sweden, Switzerland, Taiwan, Thailand, Turkey, United Kingdom, United States, Unknown Location
Active Clinical Trial Count: 82
Highest Development Phases
Phase 3: Adenocarcinoma|Breast Cancer|Gastrointestinal Cancer|Head and Neck Cancer|Non-Small-Cell Lung Cancer|Pancreatic Cancer|Prostate Cancer|Squamous Cell Carcinoma|Triple Negative Breast Cancer
Phase 2: Anus Cancer|Bladder Cancer|Cervical Cancer|Colorectal Cancer|Esophageal Cancer|Melanoma|Muscle Cancer|Neuroendocrine Carcinoma|Oncology Solid Tumor Unspecified|Ovarian Cancer|Renal Cell Carcinoma|Sarcoma|Small Cell Lung Cancer|Transitional Cell Carcinoma|Uterine Cancer
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
TRIPLE-SWITCH | P3 |
Not yet recruiting |
Prostate Cancer|Adenocarcinoma |
2031-03-14 |
|
CAPItello-280 | P3 |
Active, not recruiting |
Prostate Cancer |
2028-07-25 |
|
NCT05616624 | P2 |
Recruiting |
Non-Small-Cell Lung Cancer |
2027-12-31 |
|
CP-MGD019-02 | P2 |
Unknown Status |
Prostate Cancer |
2027-09-01 |