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Palifosfamide

Alternative Names: palifosfamide, zio-201, zio201, zio 201
Latest Update: 2024-11-23
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: Unknown

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Alaunos Therapeutics
Company Location: BOSTON MA 02129
Company CEO: Kevin S. Boyle
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Palifosfamide

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Small Cell Lung Cancer|Sarcoma

Phase 2: Sarcoma|Breast Cancer|Germinoma|Teratoma|Seminoma|Testicular Cancer

Phase 1: Thymoma|Ovarian Cancer|Oncology Unspecified|Osteosarcoma|Non-Small-Cell Lung Cancer|Testicular Cancer|Oncology Solid Tumor Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
The MATISSE Study

P3

Unknown status

Small Cell Lung Cancer

2015-06-01

2011-006134-17

P3

Completed

Small Cell Lung Cancer

2014-12-03

ATI001-201

P2

Completed

Breast Cancer

2014-12-01

IUCRO-0403

P2

Terminated

Seminoma|Testicular Cancer|Germinoma|Teratoma

2014-11-01

Recent News Events

Date

Type

Title

12/01/2021

PubMed

 Predictive Value of MRP-1 in Localized High-Risk Soft Tissue Sarcomas: A Translational Research Associated to ISG-STS 1001 Randomized Phase III Trial.

01/06/2021

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08/01/2020

PubMed

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05/01/2020

PubMed

 Design, synthesis and evaluation of targeted hypoxia-activated prodrugs applied to chondrosarcoma chemotherapy.

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