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Diquafosol

Alternative Names: diquafosol, ins365, tjo-083, tjo083
Latest Update: 2024-08-19
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: P2Y Agonist

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Ocular,Topical,Ophthalmic

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Indonesia | Korea | Malaysia | Philippines | Taiwan | Vietnam

Approved Indications: None

Known Adverse Events: None

Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Diquafosol

Countries in Clinic: Indonesia, Japan, Korea

Active Clinical Trial Count: 3

Highest Development Phases

Phase 3: Dry Eye Disease|Dry Eye Syndromes|Keratoconjunctivitis Sicca

Phase 2: Cataract

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
TJO-083-A03

P3

Recruiting

Dry Eye Syndromes|Dry Eye Disease|Keratoconjunctivitis Sicca

2024-12-31

38%
NCT06146881

P2

Recruiting

Keratoconjunctivitis Sicca|Cataract|Dry Eye Syndromes|Dry Eye Disease

2023-12-15

JapicCTI-205466

P3

Active

Keratoconjunctivitis Sicca

2021-03-31

Recent News Events

Date

Type

Title

05/06/2024

PubMed

 Effects of a Long-Acting Diquafosol Ophthalmic Solution on the Ocular Surface, Tolerability, and Usability in Dry Eye Disease.

04/25/2024

PubMed

 Effect of Long-Acting Diquafosol Sodium on Astigmatism Measurement Repeatability in Preoperative Cataract Cases with Dry Eyes: A Multicenter Prospective Study.

01/25/2024

PubMed

 Validation of an Ion-Pair Reverse Phase High-Performance Liquid Chromatography Method for the Detection of Major Components and Related Substances in Diquafosol Sodium Eye Drops.

09/09/2023

News Article

 Fresh Compressed Yeast Market 2023 Technology Advancements and Research- AngelYeast, Lesaffre Yeast, Associated British Foods

04/27/2023

News Article

 Yuyu Pharma, Dry Eye Pipeline Mechanism of Action and Pre-clinical Results Published

02/10/2023

News Article

 Dry Eye Syndrome Treatment Market to Surpass US$ 24,449.7 Million by 2030, Says Coherent Market Insights (CMI)

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