Product Description
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild-to-moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis or rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will only help you as long as you continue to take it. (Sourced from: https://www.mayoclinic.org/drugs-supplements/diclofenac-oral-route/description/drg-20069748)
Mechanisms of Action: COX2 Inhibitor,COX1 Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral,Topical,Transdermal
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Acute Pain | Pain Unspecified | Arthritis | Osteoarthritis | Acute Pain | Pain Unspecified | Contusions | Pain Unspecified | Duodenal Ulcer | Arthritis, Rheumatoid | Arthritis | Osteoarthritis
Known Adverse Events: Hypertension | Abdominal Pain | Dizziness | Headache | Pain Unspecified | Pruritus | Sinusitis | Constipation | Diarrhea | Dyspepsia | Edema | Flatulence | Insomnia | Gastritis
Company: Novartis
Company Location: BASEL V8 CH 4056
Company CEO: Vasant Narasimhan
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Australia, China, Czech Republic, Denmark, Germany, Greece, Italy, Poland, United States
Active Clinical Trial Count: 17
Highest Development Phases
Phase 3: Acute Pain|Chronic Pain|Injuries/wounds Unspecified|Keratosis, Actinic|Low Back Pain|Osteoarthritis, Knee|Pain Unspecified
Phase 1: Healthy Volunteers|Osteoarthritis
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| AMZ001 | P3 |
Not yet recruiting |
Osteoarthritis, Knee |
2025-11-01 |
|
| AMZ001 | P1 |
Recruiting |
Healthy Volunteers |
2025-04-01 |
|
| EPDICTIO75+4F01-2022 | P3 |
Unknown Status |
Acute Pain|Chronic Pain|Low Back Pain |
2025-03-31 |
|
| DITH/VER | P3 |
Unknown Status |
Acute Pain|Low Back Pain |
2025-01-02 |