Drug Search Results

Menatetrenone

Alternative Names: menatetrenone, Glakay, mk-4
Latest Update: 2024-12-16
Latest Update Note: News Article

Product Description

Mechanisms of Action: VKOR Modulator

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Japan | Taiwan | Thailand | United Kingdom

Approved Indications: None

Known Adverse Events: None

Company: Eisai
Company Location: BUNKYO-KU TOKOYO 112 M0
Company CEO: Haruo Naito
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Menatetrenone

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 4: Osteoporosis|Prediabetic State

Phase 3: Hepatocellular Carcinoma

Trial	Phase	Trial Status	Disease	Primary Completion Date
ChiCTR1900020988	N/A	Recruiting	Osteoporosis	2017-12-31
E0167-J081-191	P4	Completed	Osteoporosis	2013-01-01
Vitamin K	P4	Completed	Prediabetic State	2010-12-01
E0167-J081-551	P3	Terminated	Hepatocellular Carcinoma	None

Recent News Events

Date	Type	Title
12/16/2024	News Article	Merck Provides Update on KeyVibe and KEYFORM Clinical Development Programs Evaluating Investigational Vibostolimab and Favezelimab Fixed-Dose Combinations with Pembrolizumab
12/05/2024	News Article	Merck and Ridgeback Biotherapeutics Announce Initiation of Phase 3 Study (MOVe-NOW) Evaluating LAGEVRIO™ (molnupiravir) for the Treatment of COVID-19 in High-Risk Adults
09/25/2024	News Article	Merck Provides Update on Phase 3 KEYFORM-007 Trial Evaluating Investigational Fixed-Dose Combination of Favezelimab and Pembrolizumab for Patients With Previously Treated PD-L1 Positive Microsatellite Stable Metastatic Colorectal Cancer
05/10/2024	PubMed	Menaquinone-4 Alleviates Neurological Deficits Associated with Intracerebral Hemorrhage by Preserving Corticospinal Tract in Mice.
05/07/2024	PubMed	Effects of radical scavengers for reactive oxygen species on vitamin K-induced phototoxicity under UVA irradiation.
05/07/2024	News Article	Ligand Reports First Quarter 2024 Financial Results
04/29/2024	PubMed	Vitamin K Status Based on K1, MK-4, MK-7, and Undercarboxylated Prothrombin Levels in Adolescent and Adult Patients with Cystic Fibrosis: A Cross-Sectional Study.

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