Drug Search Results

Dapivirine

Alternative Names: dapivirine, tmc120, ring-004
Latest Update: 2024-07-04
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: NNRT Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Vaginal

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: South Africa

Approved Indications: None

Known Adverse Events: None

Company: International Partnership for Microbicides
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Dapivirine

Countries in Clinic: South Africa

Active Clinical Trial Count: 1

Highest Development Phases

Phase 1: HIV Infections

Trial	Phase	Trial Status	Disease	Primary Completion Date	Probability of Success
IPM 054	P1	Completed	HIV Infections	2024-04-02

Recent News Events

Date	Type	Title
04/18/2024	PubMed	The role of economic evaluations in advancing HIV multipurpose prevention technologies in early-stage development.
04/08/2024	PubMed	Associations between intravaginal practices and incidence of sexually transmitted infections and bacterial vaginosis among women enrolled in the dapivirine vaginal ring trial (The Ring Study) in southwestern Uganda: a retrospective secondary analysis.
03/19/2024	PubMed	Perinatal outcomes associated with pre-exposure prophylaxis for HIV prevention during pregnancy: a systematic review and meta-analysis.
08/31/2021	News Article	Johnson & Johnson and Global Partners Announce Results from Phase 2b Imbokodo HIV Vaccine Clinical Trial in Young Women in Sub-Saharan Africa
10/15/2020	News Article	Lubrizol Life Science Health Partners With Population Council on One-Year Contraceptive Vaginal System
07/24/2020	News Article	Vaginal ring for HIV prevention receives positive opinion from European regulator
06/13/2019	News Article	Pivotal ECHO Study Provides Reassuring Evidence on HIV Risk and Contraceptives

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