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Dactinomycin

Alternative Names: dactinomycin, actinomycin d, actinomycin, cosmegen
Latest Update: 2024-12-19
Latest Update Note: Clinical Trial Update

Product Description

Dactinomycin is used in combination with other medications, surgery, and/or radiation therapy to treat Wilms' tumor (a type of kidney cancer that occurs in children) and rhabdomyosarcoma (cancer that forms in muscles) in children. Dactinomycin is also used in combination with other medications to treat certain types of testicular cancer and Ewing's sarcoma (a type of cancer in bones or muscles). Dactinomycin is also used alone or in combination with other medications to treat gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant). Dactinomycin may also be used to treat certain types of cancerous tumors that are located in a specific area of the body. Dactinomycin is a type of antibiotic that is only used in cancer chemotherapy. It works by slowing or stopping the growth of cancer cells in your body. (Sourced from: https://medlineplus.gov/druginfo/meds/a682224.html)

Mechanisms of Action: Nucleic Acid Synthesis Inhibitor,Protein Synthesis Inhibitor

Novel Mechanism: No

Modality: Large Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Approved

Approved Countries: Argentina | Australia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Dominican Republic | Ecuador | Egypt | France | Germany | Greece | India | Ireland | Italy | Korea | Lithuania | Malta | Mexico | New Zealand | Pakistan | Peru | Philippines | Romania | Russia | Singapore | Slovenia | Sweden | Taiwan | Thailand | Ukraine | United Arab Emirates | United Kingdom | United States | Venezuela

Approved Indications: Myosarcoma | Oncology Solid Tumor Unspecified | Rhabdomyosarcoma | Sarcoma | Sarcoma, Ewing | Seminoma | Wilms Tumor | Oncology Unspecified | Testicular Cancer

Known Adverse Events: Alopecia | Mucositis | Anemia | Thrombocytopenia | Neutropenia

Company: ISTITUTI ORTOPEDICI RIZZOLI
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Dactinomycin

Countries in Clinic: China

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Gestational Trophoblastic Disease

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

TA7

P2

Not yet recruiting

Gestational Trophoblastic Disease

2025-08-01

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