Product Description
Dactinomycin is used in combination with other medications, surgery, and/or radiation therapy to treat Wilms' tumor (a type of kidney cancer that occurs in children) and rhabdomyosarcoma (cancer that forms in muscles) in children. Dactinomycin is also used in combination with other medications to treat certain types of testicular cancer and Ewing's sarcoma (a type of cancer in bones or muscles). Dactinomycin is also used alone or in combination with other medications to treat gestational trophoblastic tumors (a type of tumor that forms inside a woman's uterus while she is pregnant). Dactinomycin may also be used to treat certain types of cancerous tumors that are located in a specific area of the body. Dactinomycin is a type of antibiotic that is only used in cancer chemotherapy. It works by slowing or stopping the growth of cancer cells in your body. (Sourced from: https://medlineplus.gov/druginfo/meds/a682224.html)
Mechanisms of Action: Nucleic Acid Synthesis Inhibitor,Protein Synthesis Inhibitor
Novel Mechanism: No
Modality: Large Molecule
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Approved
Approved Countries: Argentina | Australia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Dominican Republic | Ecuador | Egypt | France | Germany | Greece | India | Ireland | Italy | Korea | Lithuania | Malta | Mexico | New Zealand | Pakistan | Peru | Philippines | Romania | Russia | Singapore | Slovenia | Sweden | Taiwan | Thailand | Ukraine | United Arab Emirates | United Kingdom | United States | Venezuela
Approved Indications: Myosarcoma | Oncology Solid Tumor Unspecified | Rhabdomyosarcoma | Sarcoma | Sarcoma, Ewing | Seminoma | Wilms Tumor | Oncology Unspecified | Testicular Cancer
Known Adverse Events: Alopecia | Mucositis | Anemia | Thrombocytopenia | Neutropenia
Company: ISTITUTI ORTOPEDICI RIZZOLI
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: China
Active Clinical Trial Count: 1
Highest Development Phases
Phase 2: Gestational Trophoblastic Disease
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
TA7 | P2 |
Not yet recruiting |
Gestational Trophoblastic Disease |
2025-08-01 |