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Indatuximab ravtansine

Alternative Names: indatuximab ravtansine, bt-062, bt062, bt 062
Latest Update: 2023-07-04
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: SDC Inhibitor

Novel Mechanism: Yes

Modality: Antibody

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Biotest
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Indatuximab ravtansine

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Bladder Cancer|Multiple Myeloma|Transitional Cell Carcinoma|Triple Negative Breast Cancer

Phase 1: Multiple Myeloma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
NCT01638936

P2

Completed

Multiple Myeloma

2018-10-30

53%
INTRAIN-BB (INdaTuximab RAvtansin effect IN Breast and Bladder cancer)

P2

Completed

Transitional Cell Carcinoma|Triple Negative Breast Cancer|Bladder Cancer

2017-08-04

NCT01001442

P2

Completed

Multiple Myeloma

2014-07-01

NCT00723359

P1

Completed

Multiple Myeloma

2012-04-01

Recent News Events

Date

Type

Title

07/04/2023

PubMed

 Syndecan‑1 expression is an independent favourable prognostic marker in oesophageal adenocarcinoma and represents a potential therapeutic target.

11/01/2021

PubMed

 Indatuximab ravtansine plus dexamethasone with lenalidomide or pomalidomide in relapsed or refractory multiple myeloma: a multicentre, phase 1/2a study.

01/01/2021

PubMed

 Syndecans in cancer: A review of function, expression, prognostic value, and therapeutic significance.

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