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Cotinine

Alternative Names: cotinine
Latest Update: 2024-10-23
Latest Update Note: Clinical Trial Update

Product Description

Mechanisms of Action: nAChR Binder

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Inhalant

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: National Institute on Drug Abuse (NIDA)
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Cotinine

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 4: Chronic Pain|Acute Pain

Phase 2: Tobacco Use Disorder

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
PRE_Smoking

N/A

Completed

Hypertension, Pregnancy-Induced|Pregnancy Outcomes|Pre-Eclampsia

2022-09-30

NCT04274673

P4

Unknown status

Chronic Pain|Acute Pain

2020-05-13

CANICE

N/A

Unknown status

Tobacco Use Disorder|Carcinogenesis

2017-11-01

NCT03062709

N/A

Completed

Bronchiolitis|Asthma|Bronchopulmonary Dysplasia|Tobacco Use Disorder|Pneumonia|Smoking Cessation

2017-03-30

Recent News Events

Date

Type

Title

05/15/2024

PubMed

 Relation Between Exposure to Tobacco Smoke Assessed by Serum Cotinine Concentration and Questionnaire Method, and Serum Renalase Concentration-the Importance of the Coexistence of Arterial Hypertension and Other Cardiovascular Diseases.

05/14/2024

PubMed

 Association between secondhand smoke exposure and rheumatoid arthritis in US never-smoking adults: a cross-sectional study from NHANES.

05/13/2024

PubMed

 UHPLC-MS/MS combined with microdialysis for simultaneous determination of nicotine and neurotransmitter metabolites in the rat hippocampal brain region: application to pharmacokinetic and pharmacodynamic study.

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