Product Description
Clobetasol topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various scalp and skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes). Clobetasol is in a class of medications called corticosteroids.
Mechanisms of Action: NRF2 Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Topical
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Singapore | Slovakia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Acneiform Eruptions | Dermatitis | Dermatitis, Allergic Contact | Dermatitis, Contact | Dermatitis, Perioral | Folliculitis | Hypertrichosis | Hypopigmentation | Miliaria | Rosacea | Oral Manifestations | Psoriasis | Skin Manifestations
Known Adverse Events: Erythema | Folliculitis
Company: Galderma
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Spain
Active Clinical Trial Count: 3
Highest Development Phases
Phase 3: Capsule Opacification|Cataract|Inflammation
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
CLOSE-3 | P3 |
Recruiting |
Capsule Opacification|Cataract|Inflammation |
2025-12-31 |
|
CLOBOF3-17IA03 | P3 |
Unknown Status |
Inflammation |
2025-07-31 |
|
CLOSE-3 | P3 |
Active, not recruiting |
Inflammation |
2024-05-23 |