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Carbenoxolone

Alternative Names: carbenoxolone
Clinical Status: Inactive
Latest Update: 2024-05-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: 11beta-HSD1 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: *

Approval Status: Not Approved

Approved Countries: Dominican Republic | Hong Kong | Hungary | India | Ireland | Malaysia | New Zealand | Peru | Philippines | Portugal | Spain | Taiwan | United Arab Emirates | United Kingdom

Approved Indications: None

Known Adverse Events: None

Company: University Hospitals Birmingham NHS Trust
Company Location:
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Recent & Upcoming Milestones

Highest Development Phases

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

Latest Trial Update Date

Data Updated
2006-003426-28

P2

Terminated

Unknown

2011-02-08

2022-03-12

Treatments

Recent News Events

Date

Type

Title

05/01/2024

PubMed

 Phosphorylation-dependent allosteric regulation of Cx43 gap junction inhibitor potency.

04/30/2024

PubMed

 Carbenoxolone mitigates extensive fibrosis formation in PLP-induced EAE model and multiple sclerosis serum-exposed pericyte culture.

03/01/2024

PubMed

 Isolation and microbial transformation of tea sapogenin from seed pomace of Camellia oleifera with anti-inflammatory effects.

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