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Cangrelor

Alternative Names: cangrelor, Kengreal
Latest Update: 2024-12-07
Latest Update Note: Clinical Trial Update

Product Description

Cangrelor (AR-C69931MX) is an intravenous, direct-acting and reversible P2Y(12) receptor antagonist. Cangrelor has a rapid onset and offset of action and achieves significantly greater degrees of platelet inhibition compared with clopidogrel.  (Sourced from: https://pubmed.ncbi.nlm.nih.gov/19814662/)

Mechanisms of Action: P2Y12 Antagonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Approved

Approved Countries: Austria | Belgium | Croatia | Czech | Denmark | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hungary | Iceland | Ireland | Italy | Latvia | Lithuania | Luxembourg | Netherlands | Norway | Poland | Portugal | Romania | Slovakia | Slovenia | Spain | Sweden | Switzerland | Ukraine | United Kingdom | United States

Approved Indications: Coronary Thrombosis | Myocardial Infarction | Thrombosis

Known Adverse Events: Injuries/wounds Unspecified

Company: Novartis
Company Location: BASEL V8 CH 4056
Company CEO: Vasant Narasimhan
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Cangrelor

Countries in Clinic: France

Active Clinical Trial Count: 1

Highest Development Phases

Phase 3: Stroke

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

REPERFUSE

P3

Recruiting

Stroke

2026-06-02

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