Product Description
Canosimibe is a derivative of the cholesterol absorption inhibitor ezetimibedesigned to be non-soluble and target the luminal surface of the GI tract. (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Canosimibe)
Mechanisms of Action: ACAT Inhibitor
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Sanofi
Company Location: PARIS I0 75008
Company CEO: Paul Hudson
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 3: Hypercholesterolemia
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
2006-7041-83/hah | N/A |
Not yet recruiting |
Depressive Disorder |
2018-10-15 |
|
2008-002849-23 | P3 |
Completed |
Hypercholesterolemia |
2010-06-04 |
|
2008-001550-41 | P3 |
Completed |
Hypercholesterolemia |
2009-06-17 |
|
EFC6910 | P3 |
Terminated |
Hypercholesterolemia |
2009-06-01 |