Product Description
Injection HDM2005 is a type 1 new biological drug with global intellectual property rights developed and owned by Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. It is an antibody-conjugated drug (ADC) that targets the receptor tyrosine kinase-like orphan receptor 1 (ROR1). Preclinical studies have shown that after entering the body, the antibody portion of HDM2005 specifically binds to target cells expressing tumor antigens. After being internalized by tumor cells, the cytotoxin is released intracellularly, thus completing the killing of tumor cells. Existing data show that HDM2005 has good drugability and safety. (Sourced from: https://www.moomoo.com/news/post/39046457/huadong-medicine-000963-sz-approval-obtained-for-clinical-trial-application?level=1&data_ticket=1724423598756466)
Mechanisms of Action: ROR1 Modulator
Novel Mechanism: Yes
Modality: Antibody Drug Conjugate
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Hangzhou Sino-US Huadong Pharmaceutical Co., Ltd.
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|