Product Description
AU7-55 is an oral, highly potent and selective inhibitor targeting Tyro3, Axl and Mer (TAM) that demonstrated strong anti-cancer activity against a range of cancer cell lines. In animal models, it has shown marked anti-tumour efficacy and caused tumour regression. Moreover, AU7-55 has the potential to be developed as anti-tumour immunotherapy; it promotes anti-tumour immune responses by increasing the CD3+/CD8+ T cells in murine syngeneic models. AU7-55 is in the late stage of preclinical CMC, DMPK/Tox studies. (Sourced from: https://www.aucentra.com/drug-development-pipeline/#AU2-85)
Mechanisms of Action: TAM Inhibitor
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Aucentra
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 0: Oncology Hematological Unspecified
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