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AU14-5

Alternative Names: AU14-5
Latest Update: None
Latest Update Note: None

Product Description

AU14-5 is a highly potent oral CDK2 inhibitor that exhibits an excellent selectivity for CDK2 over a panel of 360 human protein kinases. It inhibits cancer cell proliferation and demonstrates excellent anticancer efficacy without any overt toxicity in animal models including ovarian and triple negative breast cancers, as well as leukaemia. Currently, AU14-5 is in late stage of preclinical development. (Sourced from: https://www.aucentra.com/drug-development-pipeline/#AU2-85)

Mechanisms of Action: CDK2 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Aucentra
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for AU14-5

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Highest Development Phases

Phase 0: Leukemia

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