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CDX-622

Alternative Names: CDX-622, CDX622, CDX 622
Latest Update: None
Latest Update Note: None

Product Description

CDX-622 targets two complementary pathways that drive chronic inflammation, potently neutralizing the alarmin thymic stromal lymphopoietin (TSLP) and depleting mast cells via stem cell factor (SCF) starvation. Combined neutralization of SCF and TSLP with CDX-622 is expected to simultaneously reduce tissue mast cells and inhibit Type 2 inflammatory responses to potentially offer enhanced therapeutic benefit in inflammatory and fibrotic disorders. (Sourced from: https://ir.celldex.com/news-releases/news-release-details/celldex-reports-second-quarter-2024-financial-results-and)

Mechanisms of Action: TSLP Inhibitor,C-Kit Inhibitor

Novel Mechanism: Yes

Modality: N/A

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Celldex
Company Location: HAMPTON NJ 08827
Company CEO: Anthony S. Marucci
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for CDX-622

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Highest Development Phases

Phase 0: Inflammation

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