Product Description
NOV 1701 is a synthetic compound program that directly inhibits MYC. Unlike many other Myc inhibitors that have been developed so far, NOV1701 has a new mechanism that directly inhibits the binding of Myc / Max dimers to DNA. In other words, other c-Myc inhibitors indirectly inhibit Myc by modulating the universal Leucine-Zipper protein PPI of the surrounding regulators, while NOV1701 specifically and directly inhibits Myc, a substantial target protein. While the attempt to develop other platform materials (siRNA, peptide) or synthetic compounds that were under development as Myc direct inhibitors has not been very successful, NOV1701 has been proved to be the only one with high selectivity, efficacy and safety (in vivo). (Sourced from: https://www.ncc.re.kr/main.ncc?uri=english/sub02_CancerTherapeutics)
Mechanisms of Action: Myc Inhibitor
Novel Mechanism: Yes
Modality: Peptide/Protein
Route of Administration: N/A
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: National Cancer Center Korea Onco-Innovation Unit
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 0: Oncology Hematological Unspecified
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