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SM-030

Alternative Names: SM-030, SM 030, SM030
Latest Update: 2024-08-19
Latest Update Note: Clinical Trial Update

Product Description

PKCbeta has the ability to increase melanin production by phosphorylating and increasing the activity of tyrosinase, which is the key and final enzyme in the melanin synthetic pathway. SM-030 is a first-in-class selective and potent topical PKCbeta inhibitor intended to reduce the production of epidermal melanin. (Sourced from: https://www.dermbiont.com/in-the-news/2023/5/30/dermbiont-announces-positive-data-from-a-phase-2-trial-treating-solar-lentigos-and-normalizing-pigmentation-of-the-skin-with-08-sm-030-topical-gel)

Mechanisms of Action: PKC Inhibitor

Novel Mechanism: No

Modality: N/A

Route of Administration: Topical

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: DermBiont
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for SM-030

Countries in Clinic: El Salvador

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Melanosis

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
CT-214

P2

Recruiting

Melanosis

2025-04-01

Recent News Events

Date

Type

Title

08/15/2024

News Article

 DermBiont Announces Treatment of Locally Advanced Basal Cell Carcinoma and Prevention of Basal Cell Carcinoma in Gorlin Syndrome Patients as New Lead Indications for SM-020 Following Positive Initial Phase 2a Data

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