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KME-0584

Alternative Names: KME-0584, KME0584, KME 0584
Latest Update: 2024-05-01
Latest Update Note: Clinical Trial Update

Product Description

KME-0584 is a potent and highly selective small molecule inhibitor of interleukin 1 receptor associated kinases (IRAK)1, IRAK4, and all mutations of FMS-like receptor tyrosine kinase-3 (FLT3), for the treatment of R/R AML or HR-MDS. KME-0584 is intended for oral administration as a monotherapy, and as combination therapy with azacitidine or venetoclax. (Sourced from: https://www.benzinga.com/pressreleases/24/02/b37166855/kurome-therapeutics-announces-fda-clearance-of-investigational-new-drug-ind-application-for-kme-05)

Mechanisms of Action: IRAK1 Inhibitor,IRAK4 Inhibitor,FLT3 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Kurome
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for KME-0584

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 0: Acute Myeloid Leukemia|Myelodysplastic Syndrome

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