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Budiodarone

Alternative Names: budiodarone, ati-2042, ati2042, ati 2042
Latest Update: 2024-10-16
Latest Update Note: News Article

Product Description

Budiodarone is a chemical analogue of amiodarone and shares its mixed ion channel electrophysiological properties. It has a shorter half-life than amiodarone. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/22205496/)

Mechanisms of Action: Potassium Channel Inhibitor,Sodium Channel Blocker,Calcium Channel Blocker

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: ARYx
Company Location: FREMONT CA 94555
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Atrial Fibrillation

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
PASCAL

P2

Completed

Atrial Fibrillation

2008-12-16

ATI 2042-CLN 205

P2

Completed

Atrial Fibrillation

2008-12-01

Pilot Study of ATI-2042 in PAF

P2

Unknown status

Atrial Fibrillation

2005-09-10

Recent News Events

Date

Type

Title

10/16/2024

News Article

 XYRA Announces FDA Label Guidance for Managing Atrial Fibrillation with Budiodarone and Wearable Monitoring Devices

02/26/2024

News Article

 XYRA Announces Successful FDA End of Phase 2 Meeting and Agreement on Endpoints for Approval of Budiodarone for the Management of Atrial Fibrillation

02/26/2024

News Article

 XYRA Announces Successful FDA End of Phase 2 Meeting and Agreement on Endpoints for Approval of Budiodarone for the Management of Atrial Fibrillation

03/11/2019

News Article

 Espero BioPharma Announces Tecarfarin Receives FDA Orphan Drug Designation for Patients with End Stage Renal Disease and Atrial Fibrillation

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