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Borofalan

Alternative Names: Borofalan, SPM-011, SPM 011, SPM011, borofalan (10B)
Latest Update: 2024-02-21
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: Radioactive Agent

Novel Mechanism: No

Modality: Diagnostic Agent

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Japan

Approved Indications: None

Known Adverse Events: None

Company: Cancer Intelligence Care Systems
Company Location:
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Glioma

Phase 1: Sarcoma|Melanoma|Head and Neck Cancer|Squamous Cell Carcinoma|Oncology Unspecified|Glioma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
CNCT-001/SPM-011-JAM001

N/A

Completed

Melanoma|Hemangiosarcoma

2022-12-31

ST-BNCT2001

P1

Active, not recruiting

Head and Neck Cancer|Squamous Cell Carcinoma

2022-05-31

JapicCTI-195062

P1

Unknown

Sarcoma|Melanoma

2021-12-31

JapicCTI-194742

P2

Unknown

Glioma

2020-06-30

Recent News Events

Date

Type

Title

02/21/2024

PubMed

 Safety of Boron Neutron Capture Therapy with Borofalan((10)B) and Its Efficacy on Recurrent Head and Neck Cancer: Real-World Outcomes from Nationwide Post-Marketing Surveillance.

11/21/2023

PubMed

 Proposal of recommended experimental protocols for in vitro and in vivo evaluation methods of boron agents for neutron capture therapy.

08/23/2023

PubMed

 Dose Rate Effect on Cell Survival in BNCT.

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