Drug Search Results

Arterolane

Alternative Names: arterolane, rbx-11160, rbx11160, rbx 11160
Latest Update: 2023-10-31
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: PfATP6 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: India

Approved Indications: None

Known Adverse Events: None

Company: University of Oxford
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Arterolane

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Malaria, Falciparum

Trial	Phase	Trial Status	Disease	Primary Completion Date
TACTKenya	P3	Completed	Malaria, Falciparum	2019-06-03
BAKMAL1501	P3	Withdrawn	Malaria, Falciparum	2017-06-01
RBx/MMV05-06	P2	Completed	Malaria, Falciparum	None

Recent News Events

Date	Type	Title
10/31/2023	PubMed	The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use.
08/30/2022	PubMed	Comprehensive metabolite identification study of arterolane using hydrophilic interaction liquid chromatography with quadrupole-time-of-flight mass spectrometry.
01/04/2022	PubMed	The Role of the Iron Protoporphyrins Heme and Hematin in the Antimalarial Activity of Endoperoxide Drugs.

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