Product Description
ABBV-668 is an inhibitor of receptor-interacting protein kinase 1 (RIPK1) being investigated for the treatment of several immune-mediated diseases. (Sourced from: https://www.abbvie.com/our-science/pipeline/abbv-668.html)
Mechanisms of Action: RIPK1 Inhibitor
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Company: AbbVie
Company Location: Eastern America
Company Founding Year: 2013
Additional Commercial Interests: None
Clinical Description
Countries in Clinic: Belgium, France, Poland, United States
Active Clinical Trial Count: 3
Recent & Upcoming Milestones
Highest Development Phases
Phase 2: Colitis, Ulcerative
Phase 1: Healthy Volunteers
Trial ID |
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
Latest Trial Update Date |
Data Updated |
|---|---|---|---|---|---|---|---|---|
NCT05570006 |
M21-446 | P2 |
Completed |
Colitis, Ulcerative |
2024-12-23 |
2025-01-09 |
Primary Completion Date|Primary Endpoints|Study Completion Date|Treatments|Trial Status |
|
NCT06477926 |
M25-176 | P1 |
Completed |
Healthy Volunteers |
2024-09-20 |
2024-10-09 |
Primary Completion Date|Primary Endpoints|Study Completion Date |
|
2022-501263-41-00 |
M21-446 | P2 |
Completed |
Colitis, Ulcerative |
2024-12-05 |
2025-05-02 |
Treatments |
Recent News Events
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