Product Description
Bisoprolol is used alone or in combination with other medications to treat high blood pressure. Bisoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve and decrease blood pressure. (Sourced from: https://medlineplus.gov/druginfo/meds/a693024.html)
Mechanisms of Action: ADRB1 Antagonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Japan | Jordan | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: None
Known Adverse Events: None
Company: Merck KGaA
Company Location: GERMANY HRB 6164 I8
Company CEO: Belen Garijo
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: China
Active Clinical Trial Count: 5
Highest Development Phases
Phase 3: Hypertension
Phase 2: Cardiomyopathy, Hypertrophic
Phase 1: Angina Pectoris|Angina, Stable|Coronary Disease|Healthy Volunteers|Heart Failure, Chronic|Heart Failure, Systolic|Ventricular Dysfunction, Left
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| TEMPO II | P2 |
Active, not recruiting |
Cardiomyopathy, Hypertrophic |
2025-04-11 |
|
| Darmstadt-Nantong | P1 |
Completed |
Healthy Volunteers |
2023-06-18 |
28% |
| CTR20221981 | P3 |
Not yet recruiting |
Hypertension |
None |
|
| CTR20231791 | P1 |
Not yet recruiting |
Hypertension |
None |