Product Description
ISM5411, also known as ISM012-042, is an oral, gut-restricted small molecule inhibitor of PHD1/2 for the treatment of Inflammatory Bowel Disease (“IBD”). (Sourced from: https://www1.hkexnews.hk/app/sehk/2023/105489/documents/sehk23062701667.pdf)
Mechanisms of Action: EGLN2 Inhibitor
Novel Mechanism: Yes
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: InSilico Medicine
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Australia
Active Clinical Trial Count: 1
Highest Development Phases
Phase 1: Inflammatory Bowel Diseases
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
ISM5411-101 | P1 |
Completed |
Inflammatory Bowel Diseases |
2024-09-04 |