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Acalisib

Alternative Names: acalisib, gs-9820, gs9820, gs 9820
Latest Update: 2024-05-15
Latest Update Note: PubMed Publication

Product Description

Acalisib is an inhibitor of the beta and delta isoforms of the 110 kDa catalytic subunit of class IA phosphoinositide-3 kinases (PI3K) with potential immunomodulating and antineoplastic activities.  (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Acalisib)

Mechanisms of Action: PI3K Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Gilead Sciences
Company Location: FOSTER CITY CA 94404
Company CEO: Daniel P. O’Day
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Acalisib

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Lymphocytic Chronic B-Cell Leukemia|Lymphoma, Non-Hodgkin|Diffuse Large B-Cell Lymphoma|Chronic Lymphoid Leukemia

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
GS-US-315-0102

P1

Completed

Diffuse Large B-Cell Lymphoma|Lymphoma, Non-Hodgkin|Lymphocytic Chronic B-Cell Leukemia|Chronic Lymphoid Leukemia

2016-05-01

Recent News Events

Date

Type

Title

05/15/2024

PubMed

 The potential of triplet combination therapies for patients with FLT3-ITD -mutated acute myeloid leukemia.

05/08/2024

PubMed

 Comparison of four D-dimer assays in the context of venous thromboembolism in the emergency department.

04/30/2024

PubMed

 Analysis of small-scale soil CO2 fluxes in an orange orchard under irrigation and soil conservative practices.

12/17/2021

News Article

 2021 Phosphatidylinositol 3 Kinase Delta Inhibitors Pipeline Market Research Report - ResearchAndMarkets.com

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