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Abagovomab

Alternative Names: abagovomab
Latest Update: 2013-06-05
Latest Update Note: Clinical Trial Update

Product Description

Abagovomab is a murine monoclonal anti-idiotypic antibody (molecular weight: 165-175 kDa) that functionally imitates the tumor-associated antigen, CA-125. It has been shown to be well tolerated and to induce a sustained immune response in initial Phase I and II clinical trials. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/21322756/)

Mechanisms of Action: MUC16 Inhibitor

Novel Mechanism: Yes

Modality: Antibody

Route of Administration: Subcutaneous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Menarini
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Abagovomab

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Ovarian Cancer

Phase 1: Fallopian Tube Cancer|Peritoneal Cancer|Ovarian Cancer

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
2006-002801-30

P3

Completed

Ovarian Cancer

2010-12-14

MIMOSA

P3

Terminated

Ovarian Cancer

2010-12-01

CDR0000288831

P1

Completed

Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer

2004-03-01

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