Drug Search Results
More Filters [+]

Zidovudine

Alternative Names: zidovudine, retrovir, zidovudina, trizivir
Latest Update: 2024-10-23
Latest Update Note: Clinical Trial Update

Product Description

Zidovudine (azidothymidine) is a thymidine analogue antiretroviral drug active against human immunodeficiency virus (HIV). In acquired immunodeficiency syndrome (AIDS) and AIDS-related complex (ARC) patients, orally and intravenously administered zidovudine is effective in reducing the incidence of opportunistic infections and neoplasms, increasing helper T lymphocyte numbers, and improving survival rates and quality of life. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/2661194/)

Mechanisms of Action: NRT Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Bosnia | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Israel | Italy | Korea | Latvia | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam

Approved Indications: HIV Infections | HIV Infections | HIV Infections | HIV Infections

Known Adverse Events: Headache | Anemia | Neutropenia | Anorexia | HIV Infections | Headache Disorders

Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Zidovudine

Countries in Clinic: Australia

Active Clinical Trial Count: 2

Highest Development Phases

Phase 3: HIV Infections

Phase 2: Acquired Immunodeficiency Syndrome

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

D3

P3

Active, not recruiting

HIV Infections

2026-04-03

ACTRN12621001354875

P2

Active, not recruiting

HIV Infections|Acquired Immunodeficiency Syndrome

2022-09-27

Recent News Events