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Nerinetide

Alternative Names: nerinetide
Latest Update: 2024-05-01
Latest Update Note: PubMed Publication

Product Description

Nerinetide is a 20 amino acid peptide intended for intravenous infusion to improve outcomes for people who have experienced an acute ischemic stroke. (Sourced from: https://nonoinc.ca/our-pipeline/)

Mechanisms of Action: NMDA Modulator

Novel Mechanism: Yes

Modality: Peptide/Protein

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: NoNO
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Nerinetide

Countries in Clinic: Australia, Canada, Germany, Italy, Netherlands, Norway, Singapore, Switzerland, United States

Active Clinical Trial Count: 3

Highest Development Phases

Phase 3: Brain Infarction|Ischemic Stroke

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
ESCAPE-NEXT

P3

Completed

Ischemic Stroke

2023-08-31

48%
FRONTIER

P3

Completed

Ischemic Stroke|Brain Infarction

2023-03-27

95%
ESCAPE-NEXT

P3

Active, not recruiting

Ischemic Stroke

2023-01-05

Recent News Events

Date

Type

Title

05/01/2024

PubMed

 Advances in neurovascular research: Scientific highlights from the 15th world stroke congress.

05/01/2024

PubMed

 Influence of Infarct Morphology and Patterns on Cognitive Outcomes After Endovascular Thrombectomy.

05/01/2024

PubMed

 Preclinical Replication Study of the Postsynaptic Density Protein-95 Inhibitor Nerinetide.

02/20/2020

News Article

 NoNO Inc. Reports Groundbreaking Results from the Phase 3 ESCAPE-NA1 Study of the Peptide, Nerinetide, in Acute Ischemic Stroke

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