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Vonoprazan

Alternative Names: vonoprazan, tak-438, tak 438, tak438, d-v14, d v14, dv14, voquezna triple pak, voquezna dual pak
Latest Update: 2025-04-16
Latest Update Note: Clinical Trial Update

Product Description

Takeda is developing Vonoprazan (TAKECAB) as a treatment for acid-related diseases. (Sourced from: https://www.takeda.com/newsroom/newsreleases/2015/takecab-now-available-for-the-treatment-of-acid-related-diseases-in-japan/)

Mechanisms of Action: Proton Pump Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Bangladesh | China | Colombia | Egypt | Indonesia | Japan | Korea | Malaysia | Mexico | Philippines | Russia | Taiwan | United States

Approved Indications: None

Known Adverse Events: None

Company: Takeda
Company Location: TOKYO M0 103-8668
Company CEO:
Additional Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Vonoprazan

Countries in Clinic: China, Korea, United States

Active Clinical Trial Count: 12

Highest Development Phases

Phase 3: Helicobacter Infections

Phase 2: Eosinophilic Esophagitis|Esophagitis

Phase 1: Esophagitis, Peptic|Gastroesophageal Reflux|Heartburn|Peptic Ulcer|Stomach Ulcer

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
EoE-201

P2

Not yet recruiting

Eosinophilic Esophagitis

2026-12-01

VPED-105

P1

Completed

Gastroesophageal Reflux|Esophagitis

2025-04-05

VONO-401

P1

Completed

Esophagitis|Helicobacter Infections|Gastroesophageal Reflux|Heartburn

2024-09-13

VPED-103

P1

Completed

Gastroesophageal Reflux|Esophagitis, Peptic

2024-04-16

Recent News Events

Date

Type

Title

04/03/2025

News Article

 Phathom Pharmaceuticals to Present at the 24th Annual Needham Virtual Healthcare Conference

04/01/2025

News Article

 Phathom Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

03/31/2025

News Article

 Actor and Comedian Kenan Thompson Teams Up with Phathom Pharmaceuticals to Raise Awareness About GERD and VOQUEZNA® (vonoprazan)

02/24/2025

News Article

 Phathom Pharmaceuticals to Report Fourth Quarter and Full Year 2024 Financial Results and Provide Business Update on Thursday, March 6, 2025

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