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Verucerfont

Alternative Names: verucerfont, nbi-77860, gsk561679
Latest Update: 2024-04-27
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: CRFR Antagonist

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: GlaxoSmithKline
Company Location: BRENTFORD MIDDLESEX X0 TW8 9GS
Company CEO: Emma Walmsley
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Verucerfont

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Stress Disorders, Post-Traumatic|Irritable Bowel Syndrome|Alcoholism|Depressive Disorder, Major

Phase 1: Adrenogenital Syndrome|Adrenocortical Hyperfunction|Healthy Volunteers|Phobia, Social|Adrenal Hyperplasia, Congenital|Depressive Disorder

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
NBI-77860-1401

P1

Withdrawn

Adrenogenital Syndrome|Adrenocortical Hyperfunction|Adrenal Hyperplasia, Congenital

2015-10-01

10-AA-0046

P2

Completed

Alcoholism

2015-09-01

IRB00022717

P2

Completed

Stress Disorders, Post-Traumatic

2014-08-01

AFTER

P2

Completed

Stress Disorders, Post-Traumatic

2014-06-30

Recent News Events

Date

Type

Title

04/27/2024

PubMed

 Stress-free blood sampling in minipigs: A novel method for assessing 24-h cortisol profiles and drug effects on diurnal and ultradian rhythms.

02/01/2024

PubMed

 A Neuroanatomic and Pathophysiologic Framework for Novel Pharmacological Approaches to the Treatment of Post-traumatic Stress Disorder.

02/17/2022

PubMed

 Crinecerfont Lowers Elevated Hormone Markers in Adults With 21-Hydroxylase Deficiency Congenital Adrenal Hyperplasia.

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