Product Description
Mechanisms of Action: Potassium Channel Blocker,Sodium Channel Blocker
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Intravenous,Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: Austria | Belgium | Brazil | Canada | Chile | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Estonia | European Medicines Agency | Finland | Germany | Greece | Hong Kong | Hungary | Iceland | Ireland | Israel | Italy | Latvia | Lebanon | Lithuania | Luxembourg | Netherlands | New Zealand | Norway | Poland | Portugal | Romania | Slovakia | Slovenia | South Africa | Spain | Sweden | Switzerland | United Arab Emirates | United Kingdom
Approved Indications: None
Known Adverse Events: None
Company: Advanz Pharma
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 4: Atrial Fibrillation
Phase 3: Atrial Fibrillation|Atrial Flutter|Ventricular Fibrillation|Stroke|Cardiac Arrhythmias|Heart Failure
Phase 2: Atrial Fibrillation|Atrial Flutter|Cardiac Arrhythmias|Heart Failure|Stroke
Phase 1: Healthy Volunteers
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| REB20-2257 | P3 |
Not yet recruiting |
Atrial Fibrillation |
2025-01-01 |
|
| RAFF4 Trial | P4 |
Completed |
Atrial Fibrillation |
2024-09-15 |
|
| SELECTCARFAP | P4 |
Completed |
Atrial Fibrillation |
2023-06-01 |
|
| MK-6621-049 | N/A |
Completed |
Atrial Fibrillation |
2018-04-05 |
|
| SELECTI-CARFAP | P4 |
Active, not recruiting |
Atrial Fibrillation |
2016-08-04 |
|
| Vernakalant vs.Amiodarone Comparative Effectiveness Trial | P4 |
Terminated |
Atrial Fibrillation |
2016-02-20 |
|
| MK-6621-055 | P4 |
Withdrawn |
Atrial Fibrillation |
2016-02-01 |
|
| Verna-Ibu-AF | P4 |
Completed |
Atrial Fibrillation |
2015-05-12 |
|
| Verna-Ibu-AF | P4 |
Completed |
Atrial Fibrillation |
2015-05-01 |
|
| Vernakalant Versus Flecainide | P4 |
Unknown status |
Atrial Fibrillation |
2013-08-01 |
|
| Vernakalant versus flecainide: atrial contractility | P4 |
Active, not recruiting |
Atrial Fibrillation |
2013-06-25 |
|
| MK-6621-010 AM4 | P3 |
Completed |
Atrial Fibrillation |
2012-09-01 |
|
| 2010-018374-20 | P3 |
Completed |
Atrial Fibrillation |
2012-02-20 |
|
| ACT V | P3 |
Terminated |
Atrial Fibrillation |
2010-11-01 |
|
| 2007-005625-29 | P3 |
Completed |
Atrial Fibrillation|Ventricular Fibrillation|Heart Failure|Cardiac Arrhythmias|Stroke |
2009-11-23 |
|
| AVRO | P3 |
Completed |
Atrial Fibrillation |
2009-10-01 |
|
| 2006-005072-40 | P2 |
Completed |
Stroke|Atrial Fibrillation|Heart Failure|Cardiac Arrhythmias |
2008-07-04 |
|
| ACT 4 | P3 |
Completed |
Atrial Fibrillation |
2007-01-01 |
|
| Cardiome 1235-0504 | P3 |
Completed |
Atrial Fibrillation|Atrial Flutter |
2005-06-01 |
|
| ACT I | P3 |
Completed |
Atrial Fibrillation |
2004-11-01 |
|
| Scene 2 | P3 |
Completed |
Atrial Flutter |
2004-09-01 |
|
| 1235-SR-202-AF | P2 |
Completed |
Atrial Fibrillation |
None |
|
| 1235-SR-1005 | P2 |
Completed |
Atrial Flutter|Atrial Fibrillation |
None |
|
| CTR20150665 | P1 |
Active, not recruiting |
Healthy Volunteers |
None |
|
| 2006-7041-83/hah | N/A |
Not yet recruiting |
Crohn Disease|Intestinal Diseases |
None |