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UCB-6114

Alternative Names: ucb-6114, ucb 6114, ucb6114
Latest Update: 2024-05-03
Latest Update Note: Clinical Trial Update

Product Description

Upon administration, anti-gremlin-1 antibody UCB6114 specifically targets and binds to gremlin-1, thereby neutralizing Gremlin-1.

Mechanisms of Action: GREM1 Inhibitor

Novel Mechanism: Yes

Modality: Antibody

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: UCB
Company Location: SMYRNA GA 30080
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for UCB-6114

Countries in Clinic: United Kingdom, United States

Active Clinical Trial Count: 1

Highest Development Phases

Phase 2: Oncology Solid Tumor Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
ONC001

P2

Completed

Oncology Solid Tumor Unspecified

2024-04-11

57%

Recent News Events

Date

Type

Title

07/01/2022

PubMed

 Weekly dose-dense chemotherapy in first-line epithelial ovarian, fallopian tube, or primary peritoneal cancer treatment (ICON8): overall survival results from an open-label, randomised, controlled, phase 3 trial.

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