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Vadastuximab talirine

Alternative Names: vadastuximab talirine, sgn-cd33a, vadastuximab
Latest Update: 2021-07-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: CD33 Inhibitor

Novel Mechanism: No

Modality: Antibody Drug Conjugate

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Pfizer
Company Location: NEW YORK NY 10017
Company CEO: Albert Bourla
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Vadastuximab talirine

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 3: Acute Myeloid Leukemia

Phase 2: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Preleukemia

Phase 1: Acute Myeloid Leukemia|Acute Promyelocytic Leukemia

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
SGN33A-004

P2

Terminated

Myelodysplastic Syndrome|Preleukemia

2017-11-06

2015-003482-28

P3

Terminated

Acute Myeloid Leukemia

2017-10-03

CASCADE

P3

Terminated

Acute Myeloid Leukemia

2017-10-03

SGN33A-003

P2

Terminated

Acute Myeloid Leukemia

2017-02-10

Recent News Events

Date

Type

Title

07/01/2021

PubMed

 Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy.

01/01/2021

PubMed

 CD33-Targeted Therapies: Beating the Disease or Beaten to Death?

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