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SMP-100

Alternative Names: smp-100, smp100, smp 100
Latest Update: 2024-04-01
Latest Update Note: PubMed Publication

Product Description

SMP-100 is a novel serotonin receptor 3 (5-HT3) partial agonist which has been designed to be a safe and effective therapy for irritable bowel syndrome (IBS) patients. (Sourced from: https://clinicaltrials.gov/ct2/show/NCT04296799)

Mechanisms of Action: 5-HT3 Agonist

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Chengdu SciMount Pharmatech
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for SMP-100

Countries in Clinic: China

Active Clinical Trial Count: 1

Highest Development Phases

Phase 1: Irritable Bowel Syndrome

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
CTR20221090

P1

Completed

Irritable Bowel Syndrome

2022-10-21

Recent News Events

Date

Type

Title

04/01/2024

PubMed

 Structural basis for partial agonism in 5-HT3A receptors.

04/01/2020

PubMed

 CSTI-300 (SMP-100); a Novel 5-HT(3) Receptor Partial Agonist with Potential to Treat Patients with Irritable Bowel Syndrome or Carcinoid Syndrome.

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