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Befiradol

Alternative Names: befiradol
Latest Update: 2024-09-13
Latest Update Note: Clinical Trial Update

Product Description

Befiradol (also known as NLX-112) was initially developed by Pierre Fabre as a selective serotonin-1A receptor agonist for the treatment of cancer pain and neuropathic pain. (Sourced from: https://drugs.ncats.io/drug/RAT9OHA1YH)

Mechanisms of Action: 5-HT1A Agonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Neurolixis
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Befiradol

Countries in Clinic: Sweden

Active Clinical Trial Count: 2

Highest Development Phases

Phase 2: Dyskinesia, Drug-Induced|Dyskinesias|Parkinson's Disease

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
2020-006053-22

P2

Active, not recruiting

Parkinson's Disease

2023-03-22

NLX-112-DYS-101

P2

Completed

Dyskinesia, Drug-Induced|Dyskinesias

2023-01-18

Recent News Events

Date

Type

Title

04/01/2023

PubMed

 5-HT1A agonists for levodopa-induced dyskinesia in Parkinson's disease.

01/01/2023

PubMed

 Multimodal imaging study of the 5-HT1A receptor biased agonist, NLX-112, in a model of L-DOPA-induced dyskinesia.

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