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Stiripentol

Alternative Names: stiripentol, diacomit
Latest Update: 2024-12-17
Latest Update Note: Clinical Trial Update

Product Description

Stiripentol is used along with clobazam (Onfi®) to control seizures in adults and children 2 years of age and older who have Dravet syndrome (a disorder that begins in early childhood and causes seizures and later may lead to developmental delays and changes in eating, balance, and walking). Stiripentol is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement activity in the brain. (Sourced from: https://medlineplus.gov/druginfo/meds/a618069.html)

Mechanisms of Action: GABA Agonist,Cytochrome P450 Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Australia | Austria | Belgium | Canada | Croatia | Czech | Denmark | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hungary | Iceland | Ireland | Italy | Japan | Latvia | Lithuania | Netherlands | New Zealand | Norway | Poland | Portugal | Romania | Slovakia | Slovenia | South Africa | Spain | Sweden | Switzerland | Taiwan | United Kingdom | United States

Approved Indications: None

Known Adverse Events: None

Company: Biocodex
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Stiripentol

Countries in Clinic: Belgium, Bulgaria, France, Italy

Active Clinical Trial Count: 3

Highest Development Phases

Phase 3: Hyperoxaluria, Primary

Phase 1: Kidney Failure, Chronic

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success

CRYSTAL

P3

Not yet recruiting

Hyperoxaluria, Primary

2030-08-01

47%

STP226

P3

Unknown Status

Hyperoxaluria, Primary

2028-12-04

STP237

P1

Recruiting

Kidney Failure, Chronic

2024-06-15

21%

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