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Salirasib

Alternative Names: salirasib
Latest Update: 2024-02-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: Ras Protein Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Advanz Pharma
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Salirasib

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Non-Small-Cell Lung Cancer

Phase 1: Oncology Solid Tumor Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
JapicCTI-121751

P1

Completed

Oncology Solid Tumor Unspecified

2016-02-01

CCA-FTS-201

P2

Completed

Non-Small-Cell Lung Cancer

2009-11-01

Recent News Events

Date

Type

Title

02/01/2024

PubMed

 Heat stress induces ferroptosis of porcine Sertoli cells by enhancing CYP2C9-Ras- JNK axis.

01/31/2024

PubMed

 Prevention of Protease-Induced Degradation of Desmoplakin via Small Molecule Binding.

09/07/2023

PubMed

 Lipophilic modification of salirasib modulates the antiproliferative and antimigratory activity.

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