Product Description
Mechanisms of Action: mTOR Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Not Approved
Approved Countries: None
Approved Indications: None
Known Adverse Events: None
Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 3: Osteosarcoma|Soft Tissue Cancer|Bone Cancer|Sarcoma
Phase 2: Sarcoma|Prostate Cancer|Liposarcoma|Osteosarcoma|Leiomyosarcoma|Non-Small-Cell Lung Cancer|Breast Cancer|Endometrial Cancer|Oncology Unspecified|Myelodysplastic Syndrome|Myeloid Leukemia|Lymphoma|Myelofibrosis
Phase 1: Sarcoma|Glioblastoma|Lymphoma|Gliosarcoma|Oncology Solid Tumor Unspecified|Glioma|Multiple Myeloma|Ovarian Cancer|Endometrial Cancer|Heart Cancer|Oncology Unspecified|Breast Cancer|Prostate Cancer|Non-Small-Cell Lung Cancer|Colorectal Cancer|Hepatic Insufficiency|Fallopian Tube Cancer|Primary Central Nervous System Lymphoma|Peritoneal Cancer|Liver Failure
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
IoNIR-002 | N/A |
Not yet recruiting |
Coronary Artery Disease|Coronary Stenosis |
2026-09-01 |
|
CHAMPIONSHIP | N/A |
Recruiting |
Peripheral Arterial Disease |
2025-08-30 |
|
IonMAN | N/A |
Active, not recruiting |
Coronary Disease|Non-ST Elevated Myocardial Infarction|Coronary Stenosis |
2024-09-30 |
|
EluNIR-005 | N/A |
Completed |
Myocardial Ischemia|Coronary Stenosis |
2021-11-02 |