Product Description
Ribavirin, a broad spectrum, non-interferon-inducing virustatic chemotherapeutic agent, demonstrates activity against a wide range of RNA and DNA viruses, including the retrovirus known to cause the acquired immune deficiency syndrome. (Sourced from: https://pubmed.ncbi.nlm.nih.gov/3021519/)
Mechanisms of Action: IMPDH Inhibitor
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Australia | Austria | Bangladesh | Belgium | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Egypt | Estonia | European Medicines Agency | Finland | France | Germany | Greece | Hong Kong | Hungary | Iceland | India | Indonesia | Ireland | Italy | Japan | Jordan | Korea | Latvia | Lithuania | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Singapore | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Liver Cirrhosis | Hepatitis | Hepatitis, Chronic | Hepatitis C | Hepatitis C, Chronic | Hepatitis | Hepatitis, Chronic | Hepatitis C | Hepatitis C, Chronic | HIV Infections
Known Adverse Events: Headache | Erythema | Anemia | Anemia, Hemolytic | Neutropenia | Myalgia | Anorexia | Asthenia
Company: Merck
Company Location: KENILWORTH NJ 07033
Company CEO: Robert M. Davis
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: Taiwan
Active Clinical Trial Count: 2
Highest Development Phases
Phase 3: Hepatitis C, Chronic
Phase 1: Hepatitis A
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
2015-000111-41 | P3 |
Completed |
Hepatitis C, Chronic |
2023-05-01 |
|
A20-102 | P1 |
Completed |
Hepatitis A|Hepatitis C, Chronic |
2022-07-18 |
21% |