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Elifactant

Alternative Names: elifactant, chf-5633, chf5633, chf 5633
Latest Update: 2024-04-29
Latest Update Note: PubMed Publication

Product Description

For Treatment of respiratory distress syndrome (RDS) in pre-term babies (Sourced from: https://searchusan.ama-assn.org/usan/documentDownload?uri=/unstructured/binary/usan/elifactant.pdf)

Mechanisms of Action: Unknown

Novel Mechanism: No

Modality: Peptide/Protein

Route of Administration: N/A

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Chiesi
Company Location:
Company CEO:
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Respiratory Distress Syndrome, Newborn|Acute Respiratory Distress Syndrome

Phase 1: Respiratory Insufficiency|Heart Failure, Chronic|Acute Respiratory Distress Syndrome|Respiratory Distress Syndrome, Newborn

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
CCD-05633AA1-02

P2

Completed

Respiratory Distress Syndrome, Newborn|Acute Respiratory Distress Syndrome

2018-05-24

47%
2011-001331-22

P1

Completed

Respiratory Insufficiency|Heart Failure, Chronic

2015-01-23

CCD-1011-PR-0059

P1

Completed

Acute Respiratory Distress Syndrome|Respiratory Distress Syndrome, Newborn

2015-01-23

Recent News Events

Date

Type

Title

04/29/2024

PubMed

 The Synthetic Surfactant CHF5633 Restores Lung Function and Lung Architecture in Severe Acute Respiratory Distress Syndrome in Adult Rabbits.

02/01/2023

PubMed

 Efficacy of synthetic surfactant (CHF5633) bolus and/or lavage in meconium-induced lung injury in ventilated newborn rabbits.

01/01/2021

PubMed

 Impact of synthetic surfactant CHF5633 with SP-B and SP-C analogues on lung function and inflammation in rabbit model of acute respiratory distress syndrome.

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