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Aprutumab ixadotin

Alternative Names: aprutumab ixadotin, bay-1187982, bay1187982, bay 1187982
Latest Update: 2017-07-12
Latest Update Note: Clinical Trial Update

Product Description

Aprutumab ixadotin (BAY 1187982) is the first antibodyÐdrug conjugate (ADC) to target FGFR2 and the first to use a novel auristatin-based payload. (Sourced from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797631/)

Mechanisms of Action: FGFR Binder

Novel Mechanism: Yes

Modality: Antibody Drug Conjugate

Route of Administration: Intravenous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Bayer
Company Location: LEVERKUSEN 2M D-51368
Company CEO: Werner Baumann
Additional Commercial Interests: None

Clinical Description

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Oncology Solid Tumor Unspecified

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
FGFR2

P1

Terminated

Oncology Solid Tumor Unspecified

2016-07-27

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