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MEDI-4212

Alternative Names: medi-4212, medi4212, medi 4212
Latest Update: 2014-12-30
Latest Update Note: Clinical Trial Update

Product Description

Our results thus indicate that MEDI4212 is a novel, high affinity antibody that binds specifically to IgE and prevents IgE binding to its receptors. MEDI4212 effectively depleted free-IgE from human sera ex vivo to a level (1 IU/mL) anticipated to provide optimal IgE suppression in severe asthma patients. a novel high affinity anti-IgE antibody (MEDI4212) with potential to treat a broad severe asthma patient population (Sourced from: https://pubmed.ncbi.nlm.nih.gov/24583620/)

Mechanisms of Action: IgE Antagonist

Novel Mechanism: No

Modality: Antibody

Route of Administration: Subcutaneous

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: AstraZeneca
Company Location: CAMBRIDGE X0 CB2 0AA
Company CEO: Pascal Soriot
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for MEDI-4212

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Rhinitis, Allergic|Asthma, Allergic|Dermatitis, Atopic

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
CD-RI-MEDI4212-1085

P1

Completed

Asthma, Allergic|Dermatitis, Atopic|Rhinitis, Allergic

2013-06-01

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