Product Description
Phytonadione (vitamin K1) is a medication used to treat and manage vitamin K deficiency, which is a significant risk factor for intracranial hemorrhage and other bleeds. (Sourced from: https://www.ncbi.nlm.nih.gov/books/NBK557622/)
Mechanisms of Action: Vitamin K Agonist
Novel Mechanism: No
Modality: Small Molecule
Route of Administration: Oral,Injection
FDA Designation: None *
Approval Status: Approved
Approved Countries: Algeria | Argentina | Australia | Austria | Bangladesh | Belgium | Brazil | Bulgaria | Canada | Chile | China | Colombia | Croatia | Cyprus | Czech | Denmark | Dominican Republic | Ecuador | Egypt | Finland | France | Germany | Greece | Hong Kong | Hungary | India | Indonesia | Ireland | Israel | Italy | Jordan | Korea | Lebanon | Lithuania | Luxembourg | Malaysia | Malta | Mexico | Morocco | Netherlands | New Zealand | Norway | Pakistan | Peru | Philippines | Poland | Portugal | Romania | Russia | Saudi Arabia | Serbia | Slovakia | Slovenia | South Africa | Spain | Sri Lanka | Sweden | Switzerland | Taiwan | Thailand | Tunisia | Turkey | Ukraine | United Arab Emirates | United Kingdom | United States | Uruguay | Venezuela | Vietnam
Approved Indications: Biliary Fistula | Intestinal Fistula | Colitis | Enteritis | Cystic Fibrosis | Vitamin K Deficiency | Vitamin K Deficiency Bleeding | Celiac Disease | Colitis, Ulcerative | Injuries/wounds Unspecified | Vitamin D Deficiency
Known Adverse Events: Tachycardia | Hypotension | Dizziness | Dysgeusia | Dyspnea | Cyanosis | Flushing | Angioedema | Diplopia | Headache | Erythema | Urticaria | Pruritus | Anaphylaxis | Edema
Company: Elanco Animal Health
Company Location:
Company CEO:
Additonal Commercial Interests: None
Clinical Description
Countries in Clinic: China, United States
Active Clinical Trial Count: 2
Highest Development Phases
Phase 2: Glioblastoma
Phase 1: Vitamin K Deficiency Bleeding
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
---|---|---|---|---|---|
BPM31510IV-11 | P2 |
Recruiting |
Glioblastoma |
2025-02-24 |
|
CTR20232289 | P1 |
Active, not recruiting |
Vitamin K Deficiency Bleeding |
None |