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Oprozomib

Alternative Names: oprozomib
Latest Update: 2024-05-07
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: Proteasome Inhibitor

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: None

Approved Indications: None

Known Adverse Events: None

Company: Amgen
Company Location: THOUSAND OAKS CA 91320
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Oprozomib

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 2: Multiple Myeloma|Waldenstrom Macroglobulinemia|Hepatocellular Carcinoma

Phase 1: Oncology Solid Tumor Unspecified|Oncology Unspecified|Multiple Myeloma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
OPZ003

P2

Terminated

Multiple Myeloma

2019-09-23

NCT01832727

P2

Terminated

Multiple Myeloma

2019-06-25

2013-001169-18

P2

Completed

Multiple Myeloma

2019-06-25

OPZ007

P1

Terminated

Multiple Myeloma

2019-04-25

Recent News Events

Date

Type

Title

05/07/2024

PubMed

 Tissue-, region-, and gene-specific induction of microsomal epoxide hydrolase expression and activity in the mouse intestine by arsenic in drinking water.

02/15/2024

PubMed

 Potential mechanisms and drug prediction of Rheumatoid Arthritis and primary Sjögren's Syndrome: A public databases-based study.

11/01/2023

PubMed

 Proteasome inhibitors as anticancer agents.

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