Product Description
Mechanisms of Action: GLUR Antagonist,Decarboxylase Inhibitor,COMT Inhibitor
Novel Mechanism: No
Modality: N/A
Route of Administration: Intravenous
FDA Designation: None *
Approval Status: Approved
Approved Countries: Austria | Belgium | France | Germany | Hungary | Ireland | Italy | Korea | Luxembourg | Malta | Netherlands | Portugal | Slovenia | Spain | Switzerland | Turkey | United States
Approved Indications: None
Known Adverse Events: None
Company: Mayo Clinic
Company Location:
Company CEO:
Additional Commercial Interests: None
Clinical Description
Countries in Clinic:
Active Clinical Trial Count:
Highest Development Phases
Phase 3: Glioma|Stroke
Phase 2: Glioma|Melanoma|Non-Small-Cell Lung Cancer|Glioblastoma|Brain Cancer|Thyroid Cancer|Breast Cancer|Parkinson's Disease
Phase 1: Insulinoma|Congenital Hyperinsulinism|Glioblastoma
Trial |
Phase |
Trial Status |
Disease |
Primary Completion Date |
Probability of Success |
|---|---|---|---|---|---|
| NCI-2024-08915 | P2 |
Not yet recruiting |
Brain Cancer |
2029-10-08 |
|
| NCT02021604 | P1 |
Recruiting |
Congenital Hyperinsulinism|Insulinoma |
2028-01-01 |
|
| SAGA | P2 |
Recruiting |
Glioblastoma |
2027-03-02 |
|
| 2021PI203 | P3 |
Recruiting |
Glioma |
2026-08-01 |
|
| ICO-202-28 DOPACER | P2 |
Recruiting |
Melanoma|Brain Cancer|Breast Cancer|Non-Small-Cell Lung Cancer |
2026-03-03 |
|
| 2024-518721-15-00 | P3 |
Recruiting |
Stroke |
2025-05-13 |
|
| FdopaPD2 | P2 |
Active, not recruiting |
Parkinson's Disease |
2025-05-01 |
|
| FIG | N/A |
Active, not recruiting |
Glioma |
2024-05-01 |
|
| HSR190096 | P1 |
Recruiting |
Glioblastoma |
2023-12-20 |
|
| DOPACER | P2 |
Active, not recruiting |
Non-Small-Cell Lung Cancer|Melanoma|Brain Cancer|Breast Cancer |
2023-08-24 |
|
| MC167B | P2 |
Completed |
Glioma |
2020-06-16 |
|
| MC1374 | P2 |
Completed |
Glioma |
2019-07-01 |
|
| Bio 15-21 | N/A |
Terminated |
Parkinson's Disease |
2018-09-01 |
|
| F-DOPA | N/A |
Completed |
Neuroendocrine Tumors |
2015-05-01 |
|
| DOPMET | P2 |
Active, not recruiting |
Thyroid Cancer |
2010-01-19 |
|
| 09-N-0010 | N/A |
Completed |
Pure Autonomic Failure|Parkinson's Disease|Primary Dysautonomias |
None |