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Mibefradil

Alternative Names: mibefradil
Latest Update: 2024-11-01
Latest Update Note: PubMed Publication

Product Description

Mechanisms of Action: T-Calcium Channel Receptor Antagonist,L-Type Calcium Channel Antagonist,Cytochrome P450 Inhibitor,CYP3A4 Inhibitor

Novel Mechanism: Yes

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Not Approved

Approved Countries: Brazil | Chile | Ireland | Italy | Portugal | Slovenia | Venezuela

Approved Indications: None

Known Adverse Events: None

Company: Cavion, Inc.
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Mibefradil

Countries in Clinic:

Active Clinical Trial Count:

Highest Development Phases

Phase 1: Brain Stem Cancer|Pancreatic Cancer|Glioma|Ovarian Cancer|Glioblastoma

Trial

Phase

Trial Status

Disease

Primary Completion Date

Probability of Success
TAU-2014-1

P1

Completed

Glioblastoma

2017-09-29

34%
ABTC-1101 CDR0000716313

P1

Completed

Glioma|Brain Stem Cancer

2015-08-01

TAU-2011-01

P1

Completed

Pancreatic Cancer|Ovarian Cancer|Glioma

2012-06-24

31%

Recent News Events

Date

Type

Title

11/01/2024

PubMed

 Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention.

01/02/2024

PubMed

 Analgesic Buxus alkaloids with Enhanced Selectivity for the Low-Voltage-Gated Calcium Channel Cav 3.2 over Cav 3.1 through a New Binding Mode.

10/31/2023

PubMed

 Modulation of FDG Uptake by Cell Cycle Synchronization Using a T-Type Calcium Channel Inhibitor.

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