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Metirosine

Alternative Names: metirosine, metyrosine, demser
Latest Update: 2022-03-09
Latest Update Note: News Article

Product Description

Metyrosine is a methylated tyrosine, a catecholamine synthesis antagonist with antihypertensive property. Metyrosine competitively inhibits tyrosine 3-monooxygenase, an enzyme that activates molecular oxygen to catalyze the hydroxylation of tyrosine to dihydroxyphenylalanine (Dopa), an intermediate to catecholamine (dopamine, norepinephrine, and epinephrine) production.  (Sourced from: https://pubchem.ncbi.nlm.nih.gov/compound/Metyrosine)

Mechanisms of Action: Tyrosine hydroxylase Antagonist

Novel Mechanism: No

Modality: Small Molecule

Route of Administration: Oral

FDA Designation: None *

Approval Status: Approved

Approved Countries: Ireland | Japan | Slovenia | United Kingdom | United States

Approved Indications: None

Known Adverse Events: None

Company: None
Company Location:
Company CEO:
Additonal Commercial Interests: None

Clinical Description

Map of Global Clinical Trials for Metirosine

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